Advanced Cardiac Support - AOR

Key Benefits At A Glance:

• Enhances heart health and function
• Balances cholesterol levels
• Supports healthy blood pressure levels
• Improves oxygen delivery to the body
• Superior antioxidant action

Product Description:

The cardiovascular system is composed of the heart and a complex network of blood vessels, including arteries, veins and capillaries. The main function of this system is to deliver oxygen and nutrients to the cells of the body, while taking away waste products. Any dysfunction in this critical system can lead to major health problems and even death.

Advanced Cardiac Support provides a medley of well-known nutrients with established reputations for maintaining a properly functioning cardiovascular system including curcumin from turmeric root, antioxidant co-enzyme Q10, the ayurvedic herb arjuna, vitamin B6, Powergrape® whole grape extract and olive extract containing the powerful antioxidant hydroxytyrosol. This formula blends the best heart-healthy nutrients from ancient and modern medicines from around the world to provide a well-rounded heart support product.

Advanced Cardiac Support from AOR includes superior ingredients for the support of heart health, and is suitable both for individuals looking to protect and maintain the health of their heart as well as for those who already suffer from cardiovascular problems like high cholesterol, hypertension or congestive heart failure.

Research

Curcumin and the Heart

Curcumin possesses anti-inflammatory, anti-fungal, neuroprotective, metabolic and immune system enhancing properties in addition to its well-documented cardiovascular benefits. These benefits have been clinically demonstrated in studies examining the effect of curcumin supplementation on serum cholesterol and lipid peroxide levels in healthy human subjects. Results showed a 33% reduction in lipid peroxide levels along with a 29% increase in HDL cholesterol and a 12% reduction in total cholesterol.  Curcumin also inhibits and reverses cardiac hypertrophy, which often results from scar tissue formation in the cardiac muscle. Hypertrophy of the heart muscle predisposes to heart attacks and heart failure.

Co-Enzyme Q10: Unquestionably Effective
Since 1974, co-enzyme Q10 (CoQ10) has actually been approved as a drug in Japan – and later other nations – for the treatment of congestive heart failure. Placebo-controlled studies with CoQ10 (including one conducted in Italy involving 2,664 patients with congestive heart failure) have produced significantly positive results. In Canada, the evidence had become so compelling that the Natural Health Products Directorate went so far as to formally assign a monograph to CoQ10 in 2007, officially acknowledging the validity of its claims and attesting to its cardiovascular benefits.

Terminalia Arjuna: Increasing the Flow
Like CoQ10, terminalia arjuna has established a clinical presence in patients with congestive heart failure. Unlike CoQ10, which operates at the mitochondrial level, the mechanism of action for terminalia arjuna (or simply arjuna) is more directly concentrated around increasing cardiac muscle capacity. In a double-blind, placebo-controlled crossover study among patients with congestive heart failure, arjuna supplementation was able to ameliorate symptoms to such a degree that all patients had their conditions reclassified. Furthermore, arjuna increased the blood-pumping activity of their hearts by 10% and the efficiency of those hearts at emptying blood out the left ventricle (ejection fraction) rose by nearly 20%. In the treatment of angina, studies have shown arjuna supplementation to be capable of reducing the frequency of attacks by two-thirds among stable angina patients. Clinical trials have also been performed with heart attack patients – with encouraging results.

Vitamin B6: Reduces Homocysteine
A deficiency in vitamin B6 can lead to elevated homocysteine levels. Homocysteine is a toxic amino acid that is a byproduct of certain metabolic pathways in the body. High levels of this amino acid have been associated with higher incidences of coronary artery disease and increased risk of mortality from cardiovascular diseases. The conversion of homocysteine into less toxic alternatives requires the presence of vitamin B6. Supplementing with this important vitamin can help keep homocysteine levels in check, thereby helping to reduce cardiovascular disease risk. Vitamin B6 also acts to reduce inflammation. Pyridoxal-5’-phospate is a superior, active form of vitamin B6.

Grape Extract: Heart Protector
Powergrape^TM is a potent whole grape extract rich in antioxidant compounds including polyphenols, flavanols and flavanol monomers. This powerful grape extract has been clinically demonstrated to reduce oxidative stress, improve physical performance, protect the muscles from damage and to improve oxygen delivery to the cells of the body.  Grape extracts have also been studied extensively for their benefits to cardiovascular health, including their ability to reduce the oxidation of LDL cholesterol

Hydroxytyrosol: The most Powerful Antioxidant
Hydroxytyrosol is a compound present in olives. Hydroxytyrosol has the distinction of having the highest radical scavenging ability ever reported for any natural antioxidant compound. It is thought that this compound may play a key role in the better health and reduced incidence of cardiovascular disease in people eating a “Mediterranean diet”. Hyrdoxytyrosol has been shown to strongly inhibit peroxidation of LDL cholesterol, a key factor in the development of atherosclerosis. In one study involving 40 men with coronary heart disease daily consumption of raw virgin olive oil was associated with better antioxidant status, reduction in oxidized LDL and lower systolic blood pressure.

Market Trends

Turmeric
Most people know that turmeric is a healthy spice. What most people don’t know is that its anti-inflammatory and anti-cancer benefits are mainly attributed to curcumin, one of its active components that makes up only about 2% of turmeric extract. What’s more, it’s not very well absorbed.

CoQ10
CoQ10 is becoming one of the main nutrients to have crossed over from natural health circles into western medical medicine, where it is being recognized as an important heart health factor. It is quite well known now that statin medications taken for high cholesterol often deplete the heart’s CoQ10 levels, putting patients at risk for other cardiovascular complications.
Arjuna
Terminalia arjuna is not a very well-known herb on the market, but it is well-studied in modern medicine to lend support in the most severe of cardiovascular diseases.

Vitamin B6
B-Vitamins tend to be known for general health, stress or improved energy. But B6 can do more!
Grapes
Grapes are one of the most well-known heart healthy foods. Wine, in particular, accounts for much of the French paradox of high wine consumption and good heart health. In North America, grape seed extract is the most popular supplement form of grapes. But what about the rest of the grape? AOR takes the grape a step further with PowergrapeTM.
Olives
Olive oil is the most popular oil for heart health, with its benefits mainly being attributed to its monounsaturated fat content. The Mediterranean diet is high in olive oil consumption, and its partakers tend to suffer less heart disease. But olives contain other components that deserve recognition.
AOR Advantage
Advanced Cardiac Support combines science and knowledge from renowned traditions and medical systems around the world including Ayurvedic medicine, Mediterranean & French Culture, and Japanese & western medicine to form the most advanced heart health maintenance supplement. It features active, bioavailable and powerful ingredients while highlighting some of their under-appreciated health benefits.

Supplement Facts:

Non-Medicinal Ingredients: maltodextrin, potato starch, silica. Capsule: hypromellose. *Typically 10% hydroxytyrosol. †Powergrape® is a registered trademark of Naturex Inc.

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, nuts, peanuts, sesame seeds, sulphites, mustard, dairy, eggs, fish, shellfish or any animal byproduct.

Suggested Dose And Usage:

Take 1 capsule twice daily with/without food, or as directed by a qualified health care professional.

Warnings And Contraindications:

Consult a health care practitioner prior to use if you are taking blood pressure medication, antiplatelet medication, blood thinners or health products which may aggravate electrolyte imbalance, if you have a heart condition, gallstones, a bile duct obstruction, stomach ulcers, excess stomach acid, a kidney disorder, or if you are dehydrated. Consult a health care practitioner if symptoms persist or worsen, or for use beyond four weeks.
Pregnancy/Nursing: Do not take

Additional Learning And Information:

Supports Overall Cardiac Health (from AOR)

Statements about these products and health conditions have not been evaluated by Health Canada or the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent disease. For the Complete disclosure statement click here.

References

Ajay Goel, Ajaikumar B. Kunnumakkara and Bharat B. Aggarwal. Curcumin as “Curecumin”: from kitchen to clinic. Biochem Pharmacol. 2008 Feb 15;75(4):787-809.

Aruoma OI et al. Effect of Hydroxytyrosol Found in Extra Virgin Olive Oil on Oxidative DNA Damage and on Low-Density Lipoprotein Oxidation. J Agric. Food Chem. 1998; 46(12): 5181-5187.

Baggio E, Gandini R, Plancher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. Mol Aspects Med. 1994; 15(Suppl):287-294.

Dwivedi S, Agarwal MP. Antianginal and cardioprotective effects of Terminalia arjuna, an indigenous drug, in coronary artery disease. J Assoc Physicians India. 1994 Apr; 42(4): 287-9.

Epstein JA. Currying favor for the heart. J Clin Invest. 2008 Mar;118(3):850-2.

Fito M et al. Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: a randomized, crossover, controlled, clinical trial. Atherosclerosis. 2005; 181(1): 149-158.

Kim TJ et al. The inhibitory effect and mechanism of luteolin 7-glucoside on rat aortic vascular smooth muscle cell proliferation. Archives of Pharmacal Research. 2006; 29(1): 67-72.

Mink PJ et al. Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. The American Journal of Clinical Nutrition. 2007; 85(3): 895-909.

Soni, KB and Kuttan R. Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers, Indian J Physiol Pharmacol 36 (1992), pp. 273-275.