Featured Product

Natural Botanical 3-In-1 Insect Repellent – Botanec

Natural Botanical 3-In-1 Insect Repellent – Botanec An effective, DEET-free, toxin free, moisturizing, pH-balanced, botanical insect repellent that is gentle, safe, and effective for children and adults, and has a cool, refreshing citrus scent.


$19.95 4 fl oz (119ml)/can

Buy Now

Sign up for newsletter

Be Zwell informed and gain greater control of your health!  Get straight forward information, specifically for people 50 years and older, from Trusted Advisors in the Health and Wellness field.  It's FREE.

"The article on low stomach acid by Jill Hillhouse was the best, most comprehensive I have ever read on the topic.  Kudos to the writer.  This newsletter is going to get forwarded to a lot of nutrition clients."

Helen P. - BA, RNCP, ROHP


Learn : How your body works, how various conditions effect your body, how to fight disease, get health news, product information, the lastest scientific discoveries on aging and special Zwell offers.


"I have to admit, I was somewhat in the dark before I started getting your newsletter. Keep it coming."

Nancy (Fredricton, NB)

  • JUser::_load: Unable to load user with id: 72
Dr Marcus Laux
Diabetes Of The Brain - How Your Choices Effect ItPDFPrintE-mail

Alzheimer’s disease (AD) is one of the best-known and most-dreaded of all degenerative diseases. An initial diagnosis is based on people making too  frequent mistakes on simple and straightforward memory recall. The firm diagnosis of AD is based on agnosia (established memory impairment), with the presence of at least one of these cognitive deficits: apraxia (trouble with certain movements); aphasia (language impairment); or diminished executive capacity (an impaired ability to plan, sequence, organize, and reason abstractly).

Standard tests done on people who are suspected of having AD include a wide range of systems because so many factors can create cognitive impairment. Our brains are highly sensitive, and are affected quickly by almost everything that we drink, eat, say, believe, do, and are exposed to. Some AD tests are for thyroid, liver, or kidney dysfunction. Others involve blood counts to look for infections—including syphilis and HIV. While still others are checks of electrolyte, glucose, homocysteine, and vitamin B12 levels.

To date, no contagious microbe, pathogen, or parasite has stood up as either the probable cause or a major contributor—except that one study has found a potential association with Chlamydia bacteria. The ultimate cause may well be a combination of lifestyle, environment, and genetic susceptibility — which I believe to be the case with most degenerative diseases.

Brain Changes for the Worse

At autopsy, the brains of people with AD exhibit characteristic changes in the cerebral cortex, basal forebrain, and other areas. The characteristic plaques and tangles of proteins may be the result of scarring from altered proteins and abnormal cellular deposits.

The parts of the brain that are most affected are those that are largely stimulated by the neurotransmitter acetylcholine (AC) and there is a correlation between AD and a lower-than-normal AC level. Trying to correct this deficiency is one of the primary approaches of both natural and pharmaceutical medicine with varying degrees of success. The drug approach has been less than stellar, with a host (of course) of adverse effects.

Some enlightening research at the Rhode Island Hospital and Brown University Medical School has uncovered the fact that, in the early stages of AD, the brain’s insulin levels and the number of insulin receptors both diminish considerably. The insulin levels continue to plummet as AD advances into late stages by up to 80 percent. These findings are significant because previous work by the same senior researcher, Dr. Suzanne DeLaMonte, showed that insulin and other proteins are made inside the brain. This new evidence points in the direction of AD being in large part a neuroendocrine disorder.

Regulating the Brain

Alzheimer’s disease disrupts the brain’s metabolism, setting it up for inflammation and cell death which leads to cognitive malfunctions. Insulin resistance occurs when insulin and growth factor proteins (such as insulin growth factor-1, or IGF-1) have a diminished ability to bind to receptors. Without their influence, brain cells will fail and eventually die.

For the first time, the researchers at Brown University showed the clear connection that insulin and IGF-1 have to dementia. The two substances regulate the genetic expression for producing choline acetyltransferase—the enzyme pathway that is directly responsible for making AC. Higher levels increase AC production, but lower levels decrease it which is exactly what we see in Alzheimer’s. The more severe the disease, the more the patients are deficient of and resistant to insulin.

Essentially, it appears that AD may be a form of diabetes—a diabetes of the brain that is caused by an imbalanced metabolism. The imbalance creates insulin alterations and resistance that lead to growth factor deprivation, raging inflammation from poor brain energy production, and brain lesions and neuronal death from metabolic starvation.

Fixing the Fuzz

The feeling of being tired or mentally fuzzy after a meal could be a red flag that your blood sugar is too high. Research at the University of Virginia Health System showed that higher blood sugar levels are more likely to be associated with more mistakes on tests of mental function including reaction times and number subtraction. If this sounds like you, now would be the perfect time to turn the tide before fuzziness advances to full-out dementia. Stabilizing your glucose level and insulin function, and correcting your body’s imbalances, will naturally decrease inflammation. And dietary inter¬vention is the perfect place to start.

By now, you certainly know the dangers of fast food, but recent research pointed out the effect of even the occasional burger and shake. In a 15-year study of over 3,000 people between ages 18 and 30, the folks who ate at fast-food establishments more than twice a week were twice as likely to develop insulin resistance. If you find that you’re constantly on the go and don’t have time to stop for a proper meal, then make it a habit to take along energy bars or meal-replacement shakes and a bottle or two of water. There are several tasty bars out there, but watch out for added sugar— some of them are loaded with the stuff. Of course, bars that contain a lot of fruit may list a lot of sugar on the nutrition facts panel, but fruit sugar is okay. Watch for added sugar (and artificial sweeteners) in the list of ingredients.

Finally, exercise is another key to balancing your glucose regulation. A study published in the Annals of Internal Medicine tracked over 1,700 dementia-free people over age 65 for up to nine years. By the study’s end, those who had exercised three or more times a week had a significantly lower risk of developing dementia. Intensity isn’t as important as consistency. Something as simple as walking regularly is enough to help your brain.

Mental exercise is another requirement for keeping your marbles. To emphasize how much effect using your brain power actually has on improving your mind; a study in NeuroReport showed that test subjects increased the levels of brain biomarkers in their hippocampus after only five weeks of using memory-based exercises. The changes were exactly the opposite of what is seen in patients with AD.

A more recent article by the same researcher, Dr. Michael Valenzuela in Australia, combined the data from 22 worldwide studies involving almost 30,000 people. He found that those people who had high mental stimulation had a 46 percent decreased risk of dementia. The protective effect was present even in later life as long as mentally stimulating activities were undertaken.

I mentioned earlier that there is also a genetic component to AD. Research out of Johns Hopkins University reveals that people who have a gene form called APO-E2 are somewhat protected against AD, while those who have the APO-E4 form are at higher risk. However, as I’ve said before, your genes are not your destiny they’re only the stage on which your choices act. Studies following 500 identical twins showed that AD is not a directly inherited disease. For instance, one twin might get Alzheimer’s while the other twin does not. In the end, it’s all about the diet and lifestyle choices you make.


Zwell Brain Boost

Zwell Brain Boost Brain Boost is powered by cereboost to provide a fast-acting, naturally sourced mental boost.


$27.99 30 vegetarian capsules/ bottle
NPN# 80055320
Buy Now

Bar Soap Pyrenees Lavender with Cardamom - Pangea

Bar Soap Pyrenees Lavender with Cardamom - Pangea The Pyrenees Lavender with Chamomile bar soap offers a soothing, antiseptic and cleansing experience while invigorating and relieving tension.


$9.50 3.75 oz (105 g) / bar

Buy Now

Inno-Q-Nol™ Fruit Chews

Inno-Q-Nol™ Fruit Chews INNO-Q-NOL® Fruit Chews Gummies are made from Kaneka QH ubiquinol obtained through a proprietary yeast fermentation process. High-quality CoQ10 in a delicious gummy format.


$24.88 40 gummies / bottle
NPN# 80042763
Buy Now

Zwell omegaZ (Krill Oil) 1000 mg

Zwell omegaZ (Krill Oil) 1000 mg Zwell’s Krill Oil has unique properties for better bio-availability (use by bodily cells) than other fish oil products.


$67.39 60 softgels / bottle
NPN # 80034422
Buy Now

Bar Soap - Italian White Sage - Pangea

Bar Soap - Italian White Sage - Pangea The Italian White Sage with Geranium and Yarrow bar soap offers calming and healing elements while including antiseptic and antioxidant benefits to cleanse and rejuvenate your skin.


$9.50 3.75 oz (105 g) / bar

Buy Now


AOR - CurcuMIND Only free curcumin crosses the blood-brain barrier, and CurcuMIND curcumin delivers a highly bioavailable free curcumin with superior clinical results.


$86.37 90 veg capsules/bottle
NPN # 80024708
Buy Now

Zwell Joint Restore (Biovaflex)

Zwell Joint Restore (Biovaflex) Biovaflex™ is a new, all natural joint health ingredient which relieves joint pain and stiffness associated with osteoarthritis in 5 days.


$38.99 90 capsules/ bottle
NPN # 80055019
Buy Now

Adult Daily Probiotics

Adult Daily Probiotics Innovite Health Adult Daily Probiotics are designed specifically with adults in mind. It is the perfect probiotic combination for helping adults maintain a healthy digestive system.


$51.00 60 capsules / bottle
NPN# 80048138
Buy Now

Zwell BP Assist

Zwell BP Assist Zwell BP Assist helps to promote health blood pressure levels with CoQ10, grape seed extract, cocoa and magnesium.


$44.99 60 softgels/ bottle
NPN# 80043880
Buy Now

Lotion Pyrenees Lavender with Cardamom - Pangea

Lotion Pyrenees Lavender with Cardamom - Pangea This award-winning Pyrenees lavender with Cardamom Body Lotion offers invigorating antiseptic benefits while soothing and hydrating the skin.


$21.00 8.5 fl oz (240 mil) / bottle

Buy Now

Magnesium Citrate 250mg

Magnesium Citrate 250mg Helps in the maintenance of proper muscle function and tissue formation; in the development and maintenance of bones and teeth; also assists the body to metabolize carbohydrates, fats and proteins.


$16.60 100 caps / Bottle
NPN# 80011251
Buy Now

Add comment

Security code

Did you know?...

Laboratory tests show that Krill Oil has 48x the antioxidant power of regular fish oil! Learn about the many anti-inflammatory benefits of this amazing omega-3. Read More...


“Cinnamon has been used for centuries as a natural folk remedy for the treatment of diabetes in Russia, China, Korea and India,” explains Dr. Maggie Laidlaw, PhD. “The health benefits of cinnamon and its blood glucose lowering abilities have been well-documented.” Read More...


Zwell has a user community here where you can ask questions, get answers, and share ideas with fellow seniors.



 Submit >>


Healthy Tidbits

In this century, the world will have more people living into their 80s and 90s than ever before, with the number of people 80+ set to quadruple between 2000 and 2050.


Increased life expectancy is largely due to improvements in public health, and healthy ageing is linked directly to health in earlier stages of life.


Although it is natural for biological processes to decline with age, the rate at which our body’s decline is impacted by many controllable lifestyle factors such as how we eat, how we move, and how many toxic substances we are exposed to.



Zwell rewardZ screen150